The radio frequency system dedicated to the study of carbon nanotubes behaviour in RF field [articol]

Abstract

A new class of outstanding carriers, in the therapy of diseases from the last years, carbon nanotubes (CNTs), is under attention for its applicative potential in a variety of biomedical domains. In the present study, we observed that the SWCNTs, treated in a RF field could significantly improve the cellular death ratio in the liver carcinoma Hep2G cell line. The antenna designed for this study generates the RF field. The use of 13.56 MHz frequency leads to remarkable results in biomedical applications. The proposed device is capable to control the power of the electromagnetic wave and the time of exposure. The study approach is focusing also over the effect of the TF field inside the VOI (volume of interest). The conclusion, according to which the SWCNTs induce necrosis in tumor cells for different concentrations and RF power, is the most notable contribution. The experimental results lead to the idea according to which the SWCNTs provoke cell death in the absence or in the presence of the RF field. Putting the facts together, we state that the SWCNTs in the presence of the RF field contribute to the regulation of the death pathways of cancer cells.