Abstract:
A new class of outstanding carriers, in the
therapy of diseases from the last years, carbon
nanotubes (CNTs), is under attention for its applicative
potential in a variety of biomedical domains. In the
present study, we observed that the SWCNTs, treated in
a RF field could significantly improve the cellular death
ratio in the liver carcinoma Hep2G cell line. The
antenna designed for this study generates the RF field.
The use of 13.56 MHz frequency leads to remarkable
results in biomedical applications. The proposed device
is capable to control the power of the electromagnetic
wave and the time of exposure. The study approach is
focusing also over the effect of the TF field inside the
VOI (volume of interest). The conclusion, according to
which the SWCNTs induce necrosis in tumor cells for
different concentrations and RF power, is the most
notable contribution. The experimental results lead to
the idea according to which the SWCNTs provoke cell
death in the absence or in the presence of the RF field.
Putting the facts together, we state that the SWCNTs in
the presence of the RF field contribute to the regulation
of the death pathways of cancer cells.
